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The [Chemical Checker](mduranf.cargo.site) (CC) is a data-driven resource of small molecule bioactivity data. The main goal of the CC is to express data in a format that can be used off-the-shelf in daily computational drug discovery tasks. The resource is organized in **5 levels** of increasing complexity, ranging from the chemical properties of the compounds to their clinical outcomes. In between, we consider targets, off-targets, perturbed biological networks and several cell-based assays, including gene expression, growth inhibition, and morphological profiles.
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The CC is maintained by the [Structural Bioinformatics & Network Biology Laboratory](http://sbnb.irbbarcelona.org) at the Institute for Research in Biomedicine ([IRB Barcelona](http://irbbarcelona.org)). Should you have any questions, please send an email to [miquel.duran@irbbarcelona.org](miquel.duran@irbbarcelona.org) or [patrick.aloy@irbbarcelona.org](patrick.aloy@irbbarcelona.org).
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The CC is maintained by the [Structural Bioinformatics & Network Biology Laboratory](http://sbnb.irbbarcelona.org) at the Institute for Research in Biomedicine ([IRB Barcelona](http://irbbarcelona.org)). Should you have any questions, please send an email to [info@chemicalchecker.com](info@chemicalchecker.com).
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This project was first presented to the scientific community in the following paper: [Duran-Frigola et al., *Extending the small molecule similarity principle to all levels of biology* (2019)](https://biorxiv.org/content/10.1101/745703v1), and has some [related publications](publications).
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