supervised.md

 # Supervised machine learning
 
-We have developed a supervised machine learning tool called TargetMate.
+We have developed a supervised machine learning tool called Target Mate (TM). Code for this tool can be found in the CC repository: `tool/targetmate/`.
+
+TM uses CC signatures as features, similar to the use of structural descriptors used in structure-activity relationship (SAR) studies.
 
 #### Machine-learning problem
 
-* Binary classification
-* Single-output regression
+* [x] Binary classification
+* [ ] Single-output regression
 
 #### Algorithms
 
@@ -32,9 +34,9 @@ Conformal prediction
 * Stratified
 * Scaffold-based
 
-#### Model interpretation
+#### Model explanation
 
-* Shapely analysis
+* [Shapley analysis](https://github.com/slundberg/shap)
 
 #### Negative sampling